Hia, F., Yang, SF., Shichino Y., Yoshinaga M., Murakawa Y., Vandenbon A., Fukao A., Fujiwara T., Landthaler M., Natsume N., Adachi S., Iwasaki S., and Takeuchi O.:
“Codon bias confers stability to human mRNAs”
EMBO. Rep. e48220 (2019)
BioRxiv. (2018)
Padrón A., Iwasaki S., and Ingolia NT.:
“Proximity RNA labeling by APEX-Seq reveals the organization of translation initiation complexes and repressive RNA granules”
Mol. Cell. 75(4):875-887. (2019)
BioRxiv. (2018)
Han P., Mito M., Shichino Y., Hashimoto S., Udagawa T., Kohno K., Mishima Y., Inada T., Iwasaki S.:
“Genome-wide survey of ribosome collision”
BioRxiv. (2019)
Hirayama H., Matsuda T., Tsuchiya Y., Oka R., Seino J., Huang C., Nakajima K., Noda Y., Shichino Y., Iwasaki S., Suzuki T.:
“Free glycans derived from O-mannosylated glycoproteins suggest the presence of an O-glycoprotein degradation pathway in yeast”
J Biol Chem. [Epub ahead of print] (2019)
Press Release
Fujita T., Kurihara Y., and Iwasaki S.*:
“The plant translatome surveyed by ribosome profiling”
Plant Cell Physiol. 60(9):1917-1926 (2019)
Selected as "Editor's choice"
Mito M., Kadota M., Nakagawa S., and Iwasaki S.*:
“tChIP-Seq: cell-type-specific Eepigenome profiling”
J. Vis. Exp. (143) e58298. (2019)
Iwasaki S.*, Iwasaki W., Takahashi M. (equal contribution), Sakamoto A., Watanabe C., Shichino Y., Floor SN., Fujiwara K., Mito M., Dodo K., Sodeoka M., Imataka H., Honma T., Fukuzawa K., Ito T., and Ingolia NT.:
“The translation inhibitor Rocaglamide targets a bimolecular cavity between eIF4A and polypurine RNA”
Mol. Cell. 73(4):738-748. (2019)
Press Release
Akichika S., Hirano S. (equal contribution), Shichino Y., Suzuki T., Nishimasu H., Ishitani R., Sugita A., Hirose Y., Iwasaki S., Nureki O., and Suzuki T.:
“Cap-specific terminal N6-methylation of RNA by an RNA polymerase II–associated methyltransferase”
Science. 11;363(6423) (2019)
Press Release (Nikkei)
Press Release (The University of Tokyo)
Press Release (RIKEN)
Komatsu T., Yokoi S., Mito M., Fujii K., Kimura Y., Iwasaki S., and Nakagawa S.:
“UPA-Seq: Prediction of functional lncRNAs using differential sensitivity to UV crosslinking”
RNA. 24(12):1785-1802. (2018)
BioRxiv (2018)
Kurihara Y., Makita Y., Kawashima M., Fujita T., Iwasaki S., and Matsui M.:
“Transcripts from downstream alternative transcription start sites evade uORF-mediated inhibition of gene expression in Arabidopsis
Proc Natl Acad Sci U S A. 115(30):7831-7836 (2018)
Highlighted by COMMENTARY
Press Release
Mito M., Kadota M., Tanaka K., Furuta Y., Abe K., Iwasaki S.*, and Nakagawa S.:
“Cell-type specific survey of epigenetic modifications by tandem chromatin immunoprecipitation sequencing”
Sci Rep. 8:1143. (2018)
BioRxiv. (2017)
Press Release
Iwasaki S., and Tomari Y.:
“Reconstitution of RNA interference machinery”
Methods Mol Biol.1680:131-143. (2018)
Naruse K., Matsuura-Suzuki E. (equal contribution), Watanabe M., Iwasaki S.*, Tomari Y.:
“In vitro reconstitution of chaperone-mediated human RISC assembly”
RNA 24(1):6-11 (2018)
Matsuo Y., Ikeuchi K. (equal contribution), Saeki, Y., Iwasaki S., Schmidt C., Udagawa T., Sato F., Tsuchiya H., Becker T., Tanaka K., Ingolia NT., Beckmann R., and Inada T.:
“Ubiquitination of stalled ribosome triggers ribosome-associated quality control”
Nat Commun. 8(1):159 (2017)
Iwasaki S.* and Ingolia NT.:
“The Growing Toolbox for Protein Synthesis Studies”
Trends Biochem Sci. 42(8):612-624 (2017)
Ishikawa K., Makanae K., Iwasaki S., Ingolia NT., and Moriya H.:
“Post-translational dosage compensation buffers genetic perturbations to stoichiometry of protein complexes”
PLoS Genet. 13(1):e1006554 (2017)
Iwasaki S. and Ingolia NT.:
“PROTEIN TRANSLATION. Seeing translation”
Science 352(6292), 1391-2 (2016)
Iwasaki S., Floor SN., and Ingolia NT.:
“Rocaglates convert DEAD-box protein eIF4A into a sequence-selective translational repressor”
Nature 534(7608), 558-61 (2016)
Werner A., Iwasaki S., Teerikorpi N., Fedrigo I., Ingolia NT., and Rape M.:
“Cell fate determination by ubiquitin-dependent regulation of ribosome function”
Nature 525(7570), 523-7 (2015)
Iwasaki S., Sasaki MH.(equal contribution), Sakaguchi Y., Suzuki T., Tadakuma H., and Tomari Y.:
“Defining fundamental steps in the assembly of Drosophila RNAi enzyme complex”
Nature 521(7553), 533-6 (2015)
Press Release
Kwak PB., Iwasaki S. (equal contribution), and Tomari Y.:
“The microRNA pathway and cancer”
Cancer Sci. 101(11), 2309-15 (2010)
Iwasaki S., Kobayashi M. (equal contribution), Yoda M., Sakaguchi Y., Katsuma S., Suzuki T., and Tomari Y.:
“Hsc70/Hsp90 chaperone machinery mediates ATP-dependent RISC loading of small RNA duplexes”
Mol. Cell. 39(2), 292-9 (2010)
Yoda M., Kawamata T., Paroo Z., Ye X., Iwasaki S., Liu Q., and Tomari Y.:
“ATP-dependent human RISC assembly pathways”
Nat. Struct. Mol. Biol. 17(1), 17-23 (2010)
Iwasaki S., and Tomari Y.:
“Argonaute-mediated translational repression (and activation)”
Fly (Austin) 3(3), 204-6 (2009)
Iwasaki S., Kawamata T., and Tomari Y.:
Drosophila Argonaute1 and Argonaute2 employ distinct mechanisms for translational repression”
Mol Cell. 34(1), 58-67 (2009)
Journal Cover
Takeda A., Iwasaki S., Watanabe T., Utsumi M., and Watanabe Y.:
“The mechanism selecting the guide strand from small RNA duplexes is different among Argonaute proteins”
Plant Cell Physiol. 49(4), 493-500 (2008)
Iwasaki S., Takeda A., Motose H., and Watanabe Y.:
“Characterization of Arabidopsis decapping proteins AtDCP1 and AtDCP2, which are essential for post-embryonic development”
FEBS Lett. 581(13), 2455-9 (2007)
Japanese Reviews
生化学 90(2) 211‐215. (2018)
七野悠一, 岩崎信太郎:
実験医学, 35(11) 1868‐1873 (2017)
化学同人「ノンコーディングRNA RNA分子の全体像を俯瞰する」(2016)